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Figure 5 Dowling Degos disease is characterised by reticulate pigmentary changes in the skin, without skin blistering, typically on the sub exposed areas (a), and in the skin folds, such as the inframammary region (b)..

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Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Abstract

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The Ulster Medical Society, 2007



Keywords

K16

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(a) Slit lamp examination of Meesman epithelial corneal dystrophy shows myriad fine cystic lesions throughout the cornea...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
An epithelial cell in culture stained with a keratin antibody (green) reveals a dense meshwork of keratin intermediate filament bundles...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Dowling Degos disease is characterised by reticulate pigmentary changes in the skin, without skin blistering, typically on the sub exposed areas (a), and in the skin folds, such as the inframammary region (b)...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Filaggrin expression in the stratified cornified epidermis...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Hyperkeratotic disorders due to mutations in suprabasal keratins...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
In pachyonychia congenita (PC, see also Fig 7), the keratins involved are expressed to varying degrees in the oral epithelia...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Keratin genes/proteins are differentially expressed according to the many epithelial cell compartments of the human body, exemplified here by the epidermis, stained for just three keratins...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Keratin protein domain organisation...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Monilethrix is characterised by brittle hair with varying degrees of alopecia...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details
Highslide JS
Some keratins have complex expression patterns and are found in several specific subsets of epithelial cells, such as K6a, K6b, K16 and K17...

Article : Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues
Ulster Med J. 2007 May; 76(2):72-82

Click to view details