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1433B Antibody Review Page

Entry Name 1433B HUMAN
Full Protein Name 14-3-3 protein beta/alpha
Alternative Names Protein kinase C inhibitor protein 1, KCIP-1, Protein 1054
Gene Name YWHAB
Gene Synonym
UniProt ID P31946
Entrez Gene ID 7529
Ref Seq ID NM_003404
Functional Description of 1433B Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
Subcellular Location Cytoplasm, Melanosome
Tissue Specificity
Post Translation Modifications of 1433B The alpha, brain-specific form differs from the beta form in being phosphorylated.Isoform Short contains a N-acetylmethionine at position 1.
Similarity Belongs to the 14-3-3 family.
Mass (Da) 28082
1433B Homologs Human [P31946]Mouse [Q9CQV8]Rat [P35213]

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